Spinal extradural angiolipoma: report of two cases and review of the literature.

Abstract

Spinal angiolipomas are benign uncommon neoplasm composed of mature lipocytes admixed with abnormal blood vessels. They account for only 0.04-1.2% of all spinal tumors. We report two cases of lumbar extradural angiolipoma and review previously reported cases. We found 118 cases of spinal epidural angiolipoma (70 females and 48 males; age range 1.5-85 years, mean 44.03) spanning from 1890 to 2006. Prior to diagnosis 40.6% of the patients had weakness of the lower limbs. The interval between the initial symptoms and tumor diagnosis ranged from 1 day to 17 years (mean 20.2 months). Except for four cases diagnosed at autopsy, 109 patients underwent surgery and gross-total resection was performed in 79 cases (72.4%). Spinal angiolipomas are tumors containing angiomatous and lipomatous tissue, predominantly located in the mid-thoracic region. All angiolipomas show iso- or hyperintensity on T1-weighted images and hyperintensity on T2-weighted images and most lesions enhance with gadolinium administration. The treatment for spinal extradural angiolipomas is total surgical resection and no adjuvant therapy should be administered.

• Authors: Miguel Gelabert-González, Alfredo García-Allut
• Journal: European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society (Eur Spine J) Vol. 18 Issue 3 Pg. 324-35 (Mar 2009) ISSN: 1432-0932 [Electronic] Germany
• PMID: 19127373 (Publication Type: Case Reports, Journal Article, Review)

Topics

• Adolescent
• Angiolipoma (diagnostic imaging, pathology, surgery)
• Epidural Neoplasms (diagnostic imaging, pathology, surgery)
• Epidural Space (diagnostic imaging, pathology, surgery)
• Female
• Humans
• Lumbar Vertebrae (diagnostic imaging, pathology, surgery)
• Male
• Middle Aged
• Neurosurgical Procedures
• Polyradiculopathy (etiology, pathology, surgery)
• Radiography
• Sacrum (diagnostic imaging, pathology, surgery)
• Spinal Canal (diagnostic imaging, pathology, surgery)
• Spinal Neoplasms (diagnostic imaging, pathology, surgery)
• Treatment Outcome