Abstract | METHODS: RESULTS: Similar or superior efficacy of LAIV compared to TIV was reported by various studies. Respiratory symptoms were the most common adverse events following both vaccinations. Although no evidence was found of a direct causal relationship between intranasal influenza vaccine and anaphylaxis due to egg allergy, a number of cases of anaphylaxis were reported. To date, there are no studies directly comparing the frequency of anaphylactic reactions between the two vaccines. CONCLUSIONS: The safety of LAIV in individuals with unstable asthma and egg allergy has not been established and it should be avoided in these populations. For patients with unstable asthma, TIV should remain the therapy of choice.
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Authors | Neetu Vasu, Gisoo Ghaffari, Ethan T Craig, Timothy J Craig |
Journal | Therapeutic advances in respiratory disease
(Ther Adv Respir Dis)
Vol. 2
Issue 4
Pg. 193-8
(Aug 2008)
ISSN: 1753-4658 [Print] England |
PMID | 19124371
(Publication Type: Journal Article, Review)
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Chemical References |
- Influenza Vaccines
- Vaccines, Attenuated
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Topics |
- Administration, Intranasal
- Anaphylaxis
(etiology)
- Asthma
(complications)
- Egg Hypersensitivity
(complications)
- Humans
- Influenza Vaccines
(administration & dosage, adverse effects)
- Influenza, Human
(prevention & control)
- Vaccines, Attenuated
(administration & dosage, adverse effects)
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