Choroidal neovascularization in angioid streaks and pseudoxanthoma elasticum: 1 year follow-up.

Abstract

PURPOSE:

To report the efficacy of intravitreal injection of bevacizumab 1.25 mg (IVB) in the treatment of choroidal neovascularization (CNV) secondary to angioid streaks (AS).

METHODS:

Case review of two patients with CNV secondary to AS treated with three IVB with a 1-year follow up.

RESULTS:

In both patients after 1 year fluorescein angiography and optical coherence tomography showed complete inactivity of the CNV and the ophthalmologic examination revealed stabilization of the visual acuity.

CONCLUSIONS:

The IBV appeared to be an effective and safe treatment for CNV secondary to AS resulting in a long-term CNV inactivation. Further long-term studies in this type of lesion are desirable.

• Authors: D Schiano Lomoriello, M C Parravano, A Chiaravalloti, M Varano
• Journal: European journal of ophthalmology (Eur J Ophthalmol) 2009 Jan-Feb Vol. 19 Issue 1 Pg. 151-3 ISSN: 1120-6721 [Print] United States
• PMID: 19123166 (Publication Type: Case Reports, Journal Article)

Chemical References

• Angiogenesis Inhibitors
• Antibodies, Monoclonal
• Antibodies, Monoclonal, Humanized
• Vascular Endothelial Growth Factor A
• Bevacizumab

Topics

• Adult
• Angiogenesis Inhibitors (therapeutic use)
• Angioid Streaks (complications, diagnosis)
• Antibodies, Monoclonal (therapeutic use)
• Antibodies, Monoclonal, Humanized
• Bevacizumab
• Choroidal Neovascularization (diagnosis, drug therapy, etiology)
• Fluorescein Angiography
• Follow-Up Studies
• Humans
• Injections
• Male
• Pseudoxanthoma Elasticum (complications, diagnosis)
• Tomography, Optical Coherence
• Vascular Endothelial Growth Factor A (antagonists & inhibitors)
• Visual Acuity
• Vitreous Body