Abstract | BACKGROUND: METHODS: Six hundred fifty consecutive patients who underwent immediate breast reconstruction with TRAM flaps between August of 2001 and April of 2007 were included in this study. No medical prophylaxis was administered for the former 450 consecutive patients (group 1). Since February of 2006, enoxaparin was routinely given to the latter 200 consecutive patients (group 2) for 7 days, from the day of surgery. Fifty-four patients in group 1 (group 1c) and 68 patients in group 2 (group 2c) were routinely examined for asymptomatic pulmonary thromboembolism. Incidences of symptomatic and asymptomatic pulmonary thromboembolism, decreases in hemoglobin, and bleeding-related complications were compared. RESULTS: Although the incidence of symptomatic pulmonary thromboembolism did not differ significantly between groups 1 and 2 (1.8 percent versus 0 percent; p = 0.107), that of asymptomatic pulmonary thromboembolism was significantly higher in group 1c than in group 2c (16.7 percent versus 0 percent; p = 0.009). The hemoglobin decrease was significantly different (2.5 g/dl in group 1 versus 2.8 g/dl in group 2; p = 0.001), but the incidences of transfusion, hematoma, and seroma showed no statistically significant difference. CONCLUSION:
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Authors | Eun Key Kim, Jin Sup Eom, Sei Hyun Ahn, Byung Ho Son, Taik Jong Lee |
Journal | Plastic and reconstructive surgery
(Plast Reconstr Surg)
Vol. 123
Issue 1
Pg. 9-12
(Jan 2009)
ISSN: 1529-4242 [Electronic] United States |
PMID | 19116509
(Publication Type: Journal Article)
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Chemical References |
- Anticoagulants
- Enoxaparin
- Heparin, Low-Molecular-Weight
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Topics |
- Adult
- Anticoagulants
(therapeutic use)
- Breast Neoplasms
(epidemiology, surgery)
- Enoxaparin
(therapeutic use)
- Female
- Heparin, Low-Molecular-Weight
(therapeutic use)
- Humans
- Incidence
- Mammaplasty
- Prevalence
- Prospective Studies
- Pulmonary Embolism
(epidemiology, prevention & control)
- Surgical Flaps
- Treatment Outcome
- Venous Thrombosis
(diagnosis, epidemiology)
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