Abstract | BACKGROUND: RESULTS: We report here Dragon Database for Exploration of Sodium Channels in Human (DDESC), which provides comprehensive information related to sodium channels regarding different entities, such as "genes and proteins", "metabolites and enzymes", "toxins", "chemicals with pharmacological effects", "disease concepts", "human anatomy", "pathways and pathway reactions" and their potential links. DDESC is compiled based on text- and data-mining. It allows users to explore potential associations between different entities related to sodium channels in human, as well as to automatically generate novel hypotheses. CONCLUSION: DDESC is first publicly available resource where the information related to sodium channels in human can be explored at different levels. This database is freely accessible for academic and non-profit users via the worldwide web http://apps.sanbi.ac.za/ddesc.
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Authors | Sunil Sagar, Mandeep Kaur, Adam Dawe, Sundararajan Vijayaraghava Seshadri, Alan Christoffels, Ulf Schaefer, Aleksandar Radovanovic, Vladimir B Bajic |
Journal | BMC genomics
(BMC Genomics)
Vol. 9
Pg. 622
(Dec 20 2008)
ISSN: 1471-2164 [Electronic] England |
PMID | 19099596
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
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Topics |
- Databases, Genetic
- Humans
- Mutation
- Sodium Channels
(genetics)
- Software
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