Pulmonary carcinoid tumor masquerading as a synovial sarcoma.

Abstract

A rare case of pulmonary carcinoid tumor exhibiting morphologically as a monophasic synovial sarcoma is reported. The patient is a 37-year-old man who presented with shortness of breath for several weeks. The chest computed tomographic scan showed a 3.5 cm pulmonary mass in the left lower lobe.The lesion was an oval, tan nodule displaying features of monophasic synovial sarcoma. Immunohistochemical studies were performed and included a carcinoid tumor as a main differential diagnosis. Reverse transcriptase polymerase chain reaction and fluorescence in situ hybridization studies were negative for a molecular evidence of synovial sarcoma. This case further emphasizes the capacity of pulmonary carcinoid tumor cells to show various morphologic expressions even toward a mesenchymal differentiation mimicking a synovial sarcoma.

• Authors: Yun Zhong, Susan Wu, Shahriyour Andaz, Svetlana Danovich, Jen Lin
• Journal: International journal of surgical pathology (Int J Surg Pathol) Vol. 19 Issue 1 Pg. 71-4 (Feb 2011) ISSN: 1940-2465 [Electronic] United States
• PMID: 19098015 (Publication Type: Case Reports, Journal Article)

Chemical References

• Biomarkers, Tumor

Topics

• Adult
• Biomarkers, Tumor (metabolism)
• Carcinoid Tumor (metabolism, pathology)
• Diagnosis, Differential
• Humans
• Immunohistochemistry
• Lung Neoplasms (metabolism, pathology)
• Male
• Reverse Transcriptase Polymerase Chain Reaction
• Sarcoma, Synovial (metabolism, pathology)