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Diltiazem in the treatment of calcinosis in juvenile dermatomyositis.

Abstract
Subcutaneous calcifications occur in a variety of diseases, including juvenile dermatomyositis. These calcifications cause disabling symptoms that do not always respond to immunosuppressant therapy. The calcium antagonist diltiazem reduces subcutaneous calcifications in CREST syndrome and in isolated cases of children with dermatomyositis. Our study was performed to determine the effects of diltiazem when used as adjunctive therapy in children with dermatomyositis.
AuthorsT E Bertorini, J I Sebes, G M Palmieri, M Igarashi, L H Horner
JournalJournal of clinical neuromuscular disease (J Clin Neuromuscul Dis) Vol. 2 Issue 4 Pg. 191-3 (Jun 2001) ISSN: 1537-1611 [Electronic] United States
PMID19078635 (Publication Type: Journal Article)

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