[Place of inhibin B investigation in clinical andrological praxis].

Abstract

Inhibin B is a gonadal dimeric peptide, produced in men in testicular Sertolli cells. Inhibin B blood level knowledge can be a useful tool in the management of difficult diagnostic problems, such as ambiguous genitalia, the distinction between cryptorchidism and anorchidism and the hypogonadotrophic hypogonadism/delayed puberty differential diagnosis. Inhibin B measurements can help in gonadal dysgenesis evaluation, androgen insensitivity management and also in the diagnosis of some gonadal tumors. In adult men, inhibin B evaluation is helpful in the investigation of male infertility, especially in the judgment of the prognosis of testicular biopsy in in-vitro fertilization programs. Although commercial kits for inhibin B measurement are available at present, its evaluation is accessible in the Czech Republic for the time being in only very limited number of laboratory centers.

• Authors: I Porsová-Dutoit
• Journal: Vnitrni lekarstvi (Vnitr Lek) Vol. 54 Issue 11 Pg. 1059-62 (Nov 2008) ISSN: 0042-773X [Print] Czech Republic
• Vernacular Title: Význam stanovování inhibinu B v klinické andrologické praxi.
• PMID: 19069679 (Publication Type: English Abstract, Journal Article, Review)

Chemical References

• Biomarkers
• inhibin B
• Inhibins

Topics

• Biomarkers (blood)
• Gonadal Disorders (diagnosis)
• Humans
• Inhibins (blood)
• Male