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Vincristine-induced eccrine squamous syringometaplasia.

Abstract
Eccrine squamous syringometaplasia is a histologic finding associated with chemotherapy administration and other cutaneous diseases. Concentration of the chemotherapeutic agents is believed to effect toxic changes in these epithelial structures. We report the first case of vincristine-induced eccrine squamous syringometaplasia in a 12-year-old patient undergoing treatment for rhabdomyosarcoma.
AuthorsLacey Mitchell Thomas, Melinda Mohr, Michael Smith, Alan Boyd
JournalPediatric dermatology (Pediatr Dermatol) 2008 Nov-Dec Vol. 25 Issue 6 Pg. 623-5 ISSN: 1525-1470 [Electronic] United States
PMID19067868 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Antineoplastic Agents, Phytogenic
  • Vincristine
Topics
  • Antineoplastic Agents, Phytogenic (adverse effects, therapeutic use)
  • Child
  • Eccrine Glands
  • Female
  • Humans
  • Rhabdomyosarcoma (drug therapy)
  • Sweat Gland Neoplasms (chemically induced, pathology)
  • Syringoma (chemically induced, pathology)
  • Vaginal Neoplasms (drug therapy)
  • Vincristine (adverse effects, therapeutic use)

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