Abstract | OBJECTIVES: METHODS: RESULTS: Two patients and three patients complained of transient pain in Synvisc and Hyalgan groups, respectively. WOMAC scores showed significant decreases in all the groups at 6 and 12 months. There were no significant differences between the three groups with respect to improvement in WOMAC scores at 6 months. However, compared to the control group, differences between pre- and posttreatment scores at 12 months were significantly greater in the Synvisc (p=0.004) and Hyalgan (p=0.003) groups, with no significant difference between the two HA groups (p>0.05). CONCLUSION: Our findings show that AD is beneficial in osteoarthritis of the knee in patients with appropriate indications, viscosupplementation increases the efficacy of treatment, and that low- and high-molecular-weight HA preparations have similar efficacy.
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Authors | Tolga Atay, Ahmet Aslan, Metin Lütfi Baydar, Berit Ceylan, Barbaros Baykal, Vecihi Kirdemir |
Journal | Acta orthopaedica et traumatologica turcica
(Acta Orthop Traumatol Turc)
2008 Aug-Oct
Vol. 42
Issue 4
Pg. 228-33
ISSN: 1017-995X [Print] Turkey |
Vernacular Title | Gonartrozlu hastalarda artroskopik debridman sonrasi düşük ve yüksek molekül ağirlikli hiyalüronik asit uygulamalarinin etkinliği. |
PMID | 19060515
(Publication Type: English Abstract, Journal Article, Randomized Controlled Trial)
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Chemical References |
- Biocompatible Materials
- Viscosupplements
- hylan
- Hyaluronic Acid
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Topics |
- Adult
- Aged
- Arthroscopy
(methods)
- Biocompatible Materials
(administration & dosage, chemistry, therapeutic use)
- Debridement
- Female
- Humans
- Hyaluronic Acid
(administration & dosage, analogs & derivatives, chemistry, therapeutic use)
- Male
- Middle Aged
- Molecular Weight
- Osteoarthritis, Knee
(drug therapy, pathology, surgery)
- Pain
(epidemiology)
- Pain Measurement
- Prospective Studies
- Severity of Illness Index
- Treatment Outcome
- Viscosupplementation
- Viscosupplements
(administration & dosage, chemistry, therapeutic use)
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