Abstract |
An open label, comparative study to compare the efficacy of thermotherapy to meglumine antimoniate in treating cutaneous leishmaniasis patients in an operational context was carried out in Chaparral, Colombia. After enrollment patients were followed-up for up to 100 days. Per protocol and intention-to-treat cure rates for 47 patients treated using thermotherapy (one-time 50 degrees C applications for 30s) were 100 and 19%, respectively. Per protocol and intention-to-treat cure rates for meglumine antimoniate (20 mg/kg body weight administered intramuscularly for 21 d) were 78 and 23%, respectively.
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Authors | Juan Carlos Vega, Boris Fernando Sanchez, Luz Mery Montero, Rafael Montaña, Mercedes del Pilar Mahecha, Bladimir Dueñes, Angela Rocío Baron, Richard Reithinger |
Journal | Transactions of the Royal Society of Tropical Medicine and Hygiene
(Trans R Soc Trop Med Hyg)
Vol. 103
Issue 7
Pg. 703-6
(Jul 2009)
ISSN: 1878-3503 [Electronic] England |
PMID | 19059616
(Publication Type: Comparative Study, Evaluation Study, Journal Article)
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Chemical References |
- Antiprotozoal Agents
- Organometallic Compounds
- Meglumine
- Meglumine Antimoniate
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Topics |
- Adolescent
- Adult
- Antiprotozoal Agents
(economics, therapeutic use)
- Child
- Child, Preschool
- Colombia
- Female
- Humans
- Hyperthermia, Induced
(methods)
- Infant
- Infant, Newborn
- Leishmaniasis, Cutaneous
(diagnosis, economics, therapy)
- Male
- Meglumine
(economics, therapeutic use)
- Meglumine Antimoniate
- Organometallic Compounds
(economics, therapeutic use)
- Prospective Studies
- Treatment Outcome
- Young Adult
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