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Study of the correlation between clinical efficiency of impaza and serum ADMA level.

Abstract
Correlation between superlow-dose antibodies to endothelial NO synthase (Impaza) and serum level of ADMA was evaluated in a double blind placebo-controlled study. The reduction of ADMA in patients with erectile dysfunction after impaza treatment was paralleled by improvement of clinical symptoms. No clear-cut correlation between ADMA level and impaza effect was detected.
AuthorsE S Zhavbert, S A Tarasov, J L Dugina, S A Sergeeva, S I Gamidov, E B Mazo, O I Epstein
JournalBulletin of experimental biology and medicine (Bull Exp Biol Med) Vol. 145 Issue 3 Pg. 367-70 (Mar 2008) ISSN: 0007-4888 [Print] United States
PMID19039946 (Publication Type: Controlled Clinical Trial, Journal Article)
Chemical References
  • Antibodies
  • N,N-dimethylarginine
  • Arginine
  • Nitric Oxide Synthase Type III
Topics
  • Adult
  • Antibodies (therapeutic use)
  • Arginine (analogs & derivatives, blood)
  • Double-Blind Method
  • Erectile Dysfunction (drug therapy)
  • Humans
  • Male
  • Nitric Oxide Synthase Type III (immunology)

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