Meningioma in untreated congenital adrenal hyperplasia: a relationship?

Abstract

Steroid hormones have been implicated in the growth and/or development of meningiomas. A 46, XX male with untreated congenital adrenal hyperplasia who developed meningiomas is presented here. The meningiomas only expressed progesterone receptors, as most meningiomas do. The high 17-hydroxyprogesterone levels, resulting from his disease, could have played a role in the development and growth of his meningiomas.

• Authors: Annemieke C Heijboer, J Coen Netelenbos, Marinus A Blankenstein
• Journal: Journal of neuro-oncology (J Neurooncol) Vol. 92 Issue 2 Pg. 223-5 (Apr 2009) ISSN: 1573-7373 [Electronic] United States
• PMID: 19039522 (Publication Type: Case Reports, Journal Article)

Topics

• Adrenal Hyperplasia, Congenital (complications, genetics, physiopathology)
• Humans
• Male
• Meningeal Neoplasms (etiology, therapy)
• Meningioma (etiology, therapy)
• Middle Aged