Relationship between parameters of lipid peroxidation during obstructive jaundice and after bile flow restoration.

Restoration of bile flow after 9-day cholestasis in rat liver normalized the content of lipid peroxidation products. The removal of the cholestatic factor after 12-day cholestasis was not followed by recovery of these parameters. We showed that measurement of serum concentration of lipid peroxidation products in patients with cholelithiasis during the preoperative period holds promise for selection of the optimum time for surgical treatment and prediction of the risk of postoperative complications.
AuthorsL B Dudnik, A N Tsupko, M A Shupik, G G Akhaladze, E I Galperin, L V Latonova, E A Pantaz, A V Alessenko
JournalBulletin of experimental biology and medicine (Bull Exp Biol Med) Vol. 145 Issue 1 Pg. 33-6 (Jan 2008) ISSN: 0007-4888 [Print] United States
PMID19023996 (Publication Type: Journal Article)
  • Animals
  • Bile (metabolism)
  • Bile Ducts (surgery)
  • Humans
  • Jaundice, Obstructive (metabolism, surgery)
  • Lipid Peroxidation
  • Liver (pathology)
  • Rats
  • Rats, Wistar

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