Severe hyperbilirubinemia in a glucose-6-phosphate dehydrogenase-deficient preterm neonate: could prematurity be the main responsible factor?

Abstract

We report on a premature infant with glucose-6-phosphate dehydrogenase deficiency and severe hyperbilirubinemia. In this patient, all known potential hemolytic agents were excluded and no findings of hemolysis were observed. The crucial role of prematurity in the pathogenesis of this type of jaundice is discussed.

• Authors: Simonetta Costa, Maria Pia De Carolis, Daniele De Luca, Immacolata Savarese, Costantino Romagnoli
• Journal: Fetal diagnosis and therapy (Fetal Diagn Ther) Vol. 24 Issue 4 Pg. 440-3 ( 2008) ISSN: 1421-9964 [Electronic] Switzerland
• PMID: 19023210 (Publication Type: Case Reports, Journal Article)
• Copyright: Copyright 2008 S. Karger AG, Basel.

Chemical References

• Bilirubin

Topics

• Adult
• Anemia, Hemolytic, Congenital (etiology, genetics, metabolism)
• Bilirubin (blood)
• Female
• Glucosephosphate Dehydrogenase Deficiency (complications, genetics, metabolism)
• Hematocrit
• Humans
• Hyperbilirubinemia, Neonatal (etiology, genetics, metabolism)
• Infant, Newborn
• Infant, Premature
• Male
• Pregnancy
• Severity of Illness Index
• Triplets