Narrowband ultraviolet-B phototherapy in pityriasis lichenoides chronica.

Abstract

BACKGROUND:

Current knowledge about the efficacy of narrowband UVB therapy for the treatment of pityriasis lichenoides is limited.

OBJECTIVE:

The aim of this study was to investigate the efficacy of narrowband UVB therapy for the treatment of pityriasis lichenoides chronica (PLC).

METHODS:

Data were retrospectively collected following a review of patient phototherapy and medical charts, and telephone interviews were performed for follow-up information.

RESULTS:

The study included 25 patients (14 male, 11 female) with a mean age of 34 +/- 13 years. Diagnosis was confirmed by histopathological examination in 92% (n = 23) of the patients. The median duration of the disease was 24 months (range: 2-192 months). The median number of sessions until response was 25 (8 weeks) (range: 9-77 sessions), with a median cumulative dose of 15 J/cm(2) (range: 2-158 J/cm(2)). Complete response and partial response were achieved in 48% and 44% of the patients, respectively, while 8% of the patients achieved no response. In those patients for whom follow-up data were available (n = 17), 10 (58%) relapsed within a median of 9.5 months (range: 1-44 months).

CONCLUSIONS:

Our results suggest that narrowband UVB is an effective and well-tolerated treatment option for PLC.

• Authors: Sibel Ersoy-Evans, Asli Altaykan Hapa, Gonca Boztepe, Sedef Sahin, Fikret Kölemen
• Journal: The Journal of dermatological treatment (J Dermatolog Treat) Vol. 20 Issue 2 Pg. 109-13 ( 2009) ISSN: 1471-1753 [Electronic] England
• PMID: 19016063 (Publication Type: Journal Article)

Topics

• Adolescent
• Adult
• Child
• Cohort Studies
• Dose-Response Relationship, Radiation
• Female
• Follow-Up Studies
• Humans
• Male
• Middle Aged
• Patient Satisfaction
• Phototherapy (adverse effects, methods)
• Pityriasis Lichenoides (diagnosis, radiotherapy)
• Radiation Dosage
• Remission Induction
• Retrospective Studies
• Risk Assessment
• Sensitivity and Specificity
• Severity of Illness Index
• Treatment Outcome
• Ultraviolet Therapy (adverse effects, methods)
• Young Adult