Abstract | OBJECTIVES: STUDY DESIGN: A systematic review and meta-analysis were conducted. Randomized controlled studies applying Diane-35 and metformin for treating PCOS were included. The primary outcome was hirsutism. Authors of primary articles were contacted and methodological quality was evaluated. Subgroups were drawn based on treatment duration and sensitivity analysis was conducted; heterogeneity and bias are discussed. RESULTS: CONCLUSIONS:
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Authors | Zhang Jing, Xu Liang-Zhi, Wu Tai-Xiang, Tang Ying, Jia Yu-Jian |
Journal | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology
(Gynecol Endocrinol)
Vol. 24
Issue 10
Pg. 590-600
(Oct 2008)
ISSN: 1473-0766 [Electronic] England |
PMID | 19012104
(Publication Type: Comparative Study, Evaluation Study, Journal Article, Meta-Analysis, Review, Systematic Review)
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Chemical References |
- Androgen Antagonists
- Drug Combinations
- Hypoglycemic Agents
- Ethinyl Estradiol
- Cyproterone Acetate
- Cyproterone acetate, ethinyl estradiol drug combination
- Metformin
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Topics |
- Algorithms
- Androgen Antagonists
(administration & dosage, adverse effects, therapeutic use)
- Cyproterone Acetate
(administration & dosage, adverse effects, therapeutic use)
- Drug Combinations
- Ethinyl Estradiol
(administration & dosage, adverse effects, therapeutic use)
- Female
- Humans
- Hypoglycemic Agents
(administration & dosage, adverse effects, therapeutic use)
- Metformin
(administration & dosage, adverse effects, therapeutic use)
- Polycystic Ovary Syndrome
(drug therapy)
- Treatment Outcome
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