HOMEPRODUCTSSERVICESCOMPANYCONTACTFAQResearchDictionaryPharmaMobileSign Up FREE or Login

Cancer among Scandinavian women with cosmetic breast implants: a pooled long-term follow-up study.

Abstract
No increased risks of specific types of cancer following breast implantation have been consistently reported, but data on risk beyond 15 years are limited. We have pooled the results of 2 nationwide cohort studies of 3,486 Swedish and 2,736 Danish women who underwent cosmetic breast implantation between 1965 and 1993. Cancer incidence through 2002 was ascertained through nationwide cancer registries. Standardized incidence ratios (SIRs) and 95% confidence intervals (CIs) were calculated to compare cancer incidence among women with implants with women in the general population. Mean duration of follow up was 16.6 years (range 0.1-37.8 years). Over 50% of women were followed for 15 years or more after breast implantation and 13.3% for at least 25 years. There was a reduced incidence of breast cancer (SIR=0.73; 95% CI 0.58-0.90), whereas lung cancer was above expectation (SIR=1.64; 95% CI 1.10-2.36). The increased risk of lung cancer is expected due to the high prevalence of smoking among the women with implants in our study. With respect to other site-specific cancers, no significantly increased or decreased SIR was observed. This study, which includes women followed for almost 4 decades, represents the longest follow up of women with cosmetic breast implants to date. The results provide no evidence of an association between breast implants and any type of cancer.
AuthorsLoren Lipworth, Robert E Tarone, Søren Friis, Weimin Ye, Jørgen H Olsen, Olof Nyren, Joseph K McLaughlin
JournalInternational journal of cancer. Journal international du cancer (Int J Cancer) Vol. 124 Issue 2 Pg. 490-3 (Jan 15 2009) ISSN: 1097-0215 [Electronic] United States
PMID19003966 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
CopyrightCopyright (c) 2008 Wiley-Liss, Inc.
Topics
  • Adult
  • Aged
  • Breast Implantation (adverse effects)
  • Breast Implants (adverse effects)
  • Breast Neoplasms (diagnosis, epidemiology, etiology)
  • Cohort Studies
  • Denmark
  • Female
  • Follow-Up Studies
  • Humans
  • Incidence
  • Middle Aged
  • Neoplasms (diagnosis, epidemiology, etiology)
  • Risk Factors
  • Sweden

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research network!


Choose Username:
Email:
Password:
Verify Password: