Choroidal expansion during the water drinking test.

Abstract

PURPOSE:

To evaluate the correlation between intraocular pressure (IOP) rise, ocular pulse amplitude (OPA), and choroidal thickness (ChT) during the water drinking test (WDT).

METHODS:

Primary open-angle glaucoma (POAG) patients were submitted to the WDT followed by serial IOP measurements using dynamic contour tonometry (DCT), Goldman tonometry (GAT), and ChT measurements using ultrasonographic A and B-scan (USG). A control group not submitted to the test was also evaluated using DCT, GAT, and USG. Intraclass correlation coefficient (ICC) was calculated in the control group in order to assess the reproducibility of measurements. Spearman's coefficient (rho) was used to assess the correlation between the variables.

RESULTS:

Thirty eyes were included in the study. There was a significant IOP rise during the WDT using both GAT and DCT (p < 0.001). The OPA and ChT measurements also increased significantly (p < 0.001). Spearman's correlation between the OPA values and ChT measurements was significant and moderate (rho = 0.40, p = 0.005). The average increase of OPA and ChT measurements occurred 15 min before the IOP rise.

CONCLUSIONS:

There was a significant increase of OPA and ChT measurements followed by an IOP rise during the WDT. Increased choroidal volume due to hemodynamic forces may be enrolled in the mechanism of IOP elevation during this stress test.

• Authors: Carlos Gustavo Vasconcelos De Moraes, Alexandre Soares Castro Reis, Adhele Furlani de Sá Cavalcante, Milena Eimi Sano, Remo Susanna Jr
• Journal: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie (Graefes Arch Clin Exp Ophthalmol) Vol. 247 Issue 3 Pg. 385-9 (Mar 2009) ISSN: 1435-702X [Electronic] Germany
• PMID: 18987872 (Publication Type: Journal Article)

Chemical References

• Water

Topics

• Blood Pressure
• Choroid (diagnostic imaging, physiopathology)
• Diagnostic Techniques, Ophthalmological
• Drinking
• Female
• Glaucoma, Open-Angle (physiopathology)
• Humans
• Intraocular Pressure (physiology)
• Male
• Middle Aged
• Ocular Hypertension (physiopathology)
• Tonometry, Ocular
• Ultrasonography
• Water