Synthesis of 1-(heterocyclic substituted anilino)-9H-thioxanthon-9-ones and their antitumor activity.

Abstract

Some new 9H-thioxanthen-9-one incorporated into heterocyclic systems such as pyridone8, pyrazoline9, pyranone11, iminopyrane12, furopyrimidine17, imidazothiazole19, thiazole21, triazine24 and other related compounds through a para imminophenyl grouping at position-1 of the thioxanthenone ring were synthesized and tested as antitumor agents, against L 1210 leukemia in mice. Some of the new compounds showed considerable antitumor activity.

• Authors: M T Omar
• Journal: Archives of pharmacal research (Arch Pharm Res) Vol. 20 Issue 6 Pg. 610-9 (Dec 1997) ISSN: 0253-6269 [Print] Korea (South)
• PMID: 18982268 (Publication Type: Journal Article)