[Assessment of single-dose regimen for antimicrobial prophylaxis to prevent perioperative infection in urologic surgery].
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| Abstract |
A single-dose ofantimicrobial prophylaxis (AMP) was administered parenterally for prevention of perioperative infection in a total of 206 urologic surgeries including 114 endoscopic-instrumental, 92 clean, and 20 clean-contaminated procedures between January and December, 2007, and surgical site infections (SSI), urinary tract infections (UTI), and remote infections (RI) were prospectively surveyed. The definition of a single-dose of AMP allowed the administration of a second dose of an antimicrobial during a surgical procedure that exceeded 3 hours but not parenteral or oral administration at the end of the procedure, in the recovery room, or at a later time over a period of more than 24 hours. UTI was observed in 3 cases (2.7%) after endoscopic-instrumental procedures and in 1 case (5%) after clean-contaminated procedures while no case was associated with UTI in clean procedures. SSI was seen in 1 case each after clean procedures (1.1%) and after clean-contaminated procedures (5%), and RI was seen in 2 cases (2.2%) after clean procedures. A single-dose regimen of AMP was effective for prevention ofperioperative infections including SSI, UTI, and RI in endoscopic-instrumental, clean, and clean-contaminated surgical procedures in urology.
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| Authors | Shingo Yamamoto, Youzou Mitsui, Yasuo Ueda, Toru Suzuki, Yoshihide Higuchi, Jun Qiu, Takuo Maruyama, Nobuyuki Kondou, Michio Nojima, Yoshio Takesue, Hiroki Shima |
| Journal | Hinyokika kiyo. Acta urologica Japonica (Hinyokika Kiyo) Vol. 54 Issue 9 Pg. 587-91 (Sep 2008) ISSN: 0018-1994 [Print] Japan |
| PMID | 18975571 (Publication Type: English Abstract, Journal Article) |
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