[Prevention and multimodal therapy of hyperthyroidism].

Subclinical and overt hyperthyroidism have been associated with various negative clinical outcomes as for example an increased risk of atrial fibrillation or increased cardiovascular mortality, especially in old age. In order to avoid hyperthyroidism it is strongly recommended not to start any iodine containing drug therapy or to avoid application of contrast agents unless the patient presents with an unremarkable clinical course. TSH suppressive therapy for the treatment of endemic goiter or differentiated low risk thyroid carcinoma is unnecessary, since it favours the development of subclinical hyperthyroidism. Overt hyperthyroidism is treated with antithyroid drugs and/or radioiodine therapy or surgery according to the underlying disease (toxic nodular goiter, Graves' disease).
AuthorsK-D Palitzsch
JournalDer Internist (Internist (Berl)) Vol. 49 Issue 12 Pg. 1428, 1430-2, 1434-6 (Dec 2008) ISSN: 0020-9554 [Print] Germany
Vernacular TitlePrävention und multimodale Therapie der Hyperthyreose.
PMID18946641 (Publication Type: English Abstract, Journal Article, Review)
Chemical References
  • Antithyroid Agents
  • Iodine Radioisotopes
  • Thyroid Hormones
  • Antithyroid Agents (adverse effects, therapeutic use)
  • Humans
  • Hyperthyroidism (diagnosis, etiology, prevention & control, therapy)
  • Iodine Radioisotopes (therapeutic use)
  • Liver Function Tests
  • Thyroid Hormones (blood)
  • Thyroidectomy

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