Abstract |
Giant condyloma acuminatum (GCA; Buschke-Lowenstein tumor) is a human-papillomavirus-induced cauliflower-like tumor of the genitoanal region. It is characterized by its size, capability of local infiltration and high recurrence rate. We report on a 50-year-old patient presenting with a maximum finding of GCA with deep infiltration into the adductor and perineal musculature, the scrotum, the penis and the para-rectum. After performing a temporary loop colostomy, the tumor was removed by wide radical excision following plastic reconstruction with a myocutaneous gracilis flap. During a follow-up period of more than 5 years, no recurrence developed. Many treatment strategies (e.g. chemotherapy, radiation) have been published in the literature. Most authors recommend the radical surgical excision, allowing a complete histological examination and assessment of tumor-free resection margins. Despite the benign histological pattern of GCA in most cases, transformations into verrucous carcinoma and squamous-cell carcinoma have been described. In our case, the GCA seems to represent a continuum between normal condyloma acuminatum and an initial verrucous carcinoma.
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Authors | P Gholam, A Enk, W Hartschuh |
Journal | Dermatology (Basel, Switzerland)
(Dermatology)
Vol. 218
Issue 1
Pg. 56-9
( 2009)
ISSN: 1421-9832 [Electronic] Switzerland |
PMID | 18936533
(Publication Type: Case Reports, Journal Article)
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Copyright | Copyright 2008 S. Karger AG, Basel. |
Topics |
- Anus Neoplasms
(pathology, surgery, virology)
- Condylomata Acuminata
(pathology, surgery, virology)
- Human papillomavirus 6
(isolation & purification)
- Humans
- Male
- Middle Aged
- Papillomavirus Infections
(pathology, surgery, virology)
- Penile Neoplasms
(pathology, surgery, virology)
- Skin
(pathology)
- Surgical Flaps
- Treatment Outcome
- Urologic Surgical Procedures, Male
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