Effects of erosive, cariogenic or combined erosive/cariogenic challenges on human enamel: an in situ/ex vivo study.

Abstract

Individuals with cariogenic diet can also consume erosive beverages. Thus, it seems necessary to investigate a possible caries/erosion interaction. To test in situ/ex vivo a combination of these challenges, 11 subjects wore intraoral appliances containing four enamel blocks randomly assigned. In the first 2-week phase, the appliances were immersed in a cola drink 3 times/day. Two blocks were free of plaque (erosion only: EO) and two blocks were covered with plaque (erosion + plaque: EP). In the second 2-week phase, four new blocks were all covered with plaque and subjected to a sucrose solution 8 times/day. Among the four new blocks, two were also subjected to the cola drink 3 times/day (erosion + caries: EC) while the other two were not (caries only: CO). Thus, in EO, the specimens were fixed at the intraoral appliance level. In EP, EC and CO they were fixed 1.0 mm under the appliance level and covered with plastic meshes for dental plaque accumulation. Changes in wear and hardness were measured. Data were tested using ANOVA and Tukey's test (p < 0.05). Mean values of wear (microm) and change in hardness (kp/mm(2)) were: EO 4.82/310; EP 0.14/48; EC 0.34/245; CO 0.42/309. With respect to surface softening, EP and EC differed significantly from each other and from EO and CO, which did not differ significantly. EO presented significantly higher wear than the other groups. The data suggest that the presence of dental plaque can decrease the acid attack of an erosive drink and the association of erosive and cariogenic challenges showed less enamel alterations when compared to erosive or cariogenic challenges only.

• Authors: H M Honório, D Rios, C F Santos, A C Magalhães, M A R Buzalaf, M A A M Machado
• Journal: Caries research (Caries Res) Vol. 42 Issue 6 Pg. 454-9 ( 2008) ISSN: 1421-976X [Electronic] Switzerland
• PMID: 18931495 (Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
• Copyright: (c) 2008 S. Karger AG, Basel.

Chemical References

• Cariogenic Agents
• Sucrose

Topics

• Adult
• Carbonated Beverages (adverse effects)
• Cariogenic Agents (adverse effects)
• Dental Caries (complications)
• Dental Enamel (pathology)
• Dental Enamel Solubility (drug effects)
• Dental Plaque (complications)
• Female
• Hardness
• Humans
• Hydrogen-Ion Concentration
• Male
• Sucrose (adverse effects)
• Tooth Erosion (complications)
• Young Adult