[Gemfibrozil in the treatment of hyperlipoproteinemias].

Abstract

30 patients with primary hyperlipoproteinemia (type II and IV according to Fredrickson) were treated with Gemfibrosil (Gevinon--film tablets of 450 mg of "Parke-Davis Company") for a period of 45 days with a daily dose of two tablets taken with the evening meal. The results of the treatment were a decrease of the total cholesterol (with 16.34%), of triglycerides (with 34.50%), of low density lipoproteins (with 10.76%) and of very low density lipoproteins (with 49.21%) and an increase of the high density lipoproteins (with 2.34%). Gevilon was well tolerated. No side effects requiring discontinuing of the treatment were registered.

• Authors: D Monova, V Petrova, N Belovezhdov
• Journal: Vutreshni bolesti (Vutr Boles) Vol. 30 Issue 2 Pg. 56-8 ( 1991) ISSN: 0506-2772 [Print] Bulgaria
• Vernacular Title: Gemfibrozil pri ledchenie na khiperlipoproteinemiite.
• PMID: 1891900 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Lipoproteins
• Triglycerides
• Cholesterol
• Gemfibrozil

Topics

• Adult
• Aged
• Cholesterol (blood)
• Drug Evaluation
• Female
• Gemfibrozil (therapeutic use)
• Humans
• Hyperlipoproteinemia Type II (blood, drug therapy)
• Hyperlipoproteinemia Type IV (blood, drug therapy)
• Lipoproteins (blood, drug effects)
• Male
• Middle Aged
• Time Factors
• Triglycerides (blood)