Evaluation of the expression of early activation marker CD69 by CD8+ lymphocytes in HIV-infected patients.

Abstract

We studied the expression of CD69 antigen on CD8+ lymphocytes in response to nonspecific activator phytohemagglutinin in 202 patients with HIV infection. It was found that the number of CD8+CD69+ lymphocytes in HIV-infected patients increased; this parameter negatively correlated with relative and absolute content of CD4+ cells and positively correlated with IgG concentration.

• Authors: I V Isakov, L M Kurtasova
• Journal: Bulletin of experimental biology and medicine (Bull Exp Biol Med) Vol. 144 Issue 6 Pg. 810-2 (Dec 2007) ISSN: 0007-4888 [Print] United States
• PMID: 18856207 (Publication Type: Evaluation Study, Journal Article)

Chemical References

• Antigens, CD
• Antigens, Differentiation, T-Lymphocyte
• CD69 antigen
• Lectins, C-Type

Topics

• Antigens, CD (biosynthesis)
• Antigens, Differentiation, T-Lymphocyte (biosynthesis)
• CD8-Positive T-Lymphocytes (metabolism)
• HIV Infections (blood, immunology)
• Humans
• Lectins, C-Type