Abstract | OBJECTIVE: DESIGN: Parallel randomized, controlled, double-blind pilot study. PATIENTS AND METHODS: A total of 14 patients (8 women and 6 men) with post-polio syndrome participated in a 12-week muscular resistance training, 3 days/week. The patients were randomized for oral supplementation with coenzyme Q10, 200 mg/day, or placebo. Measurements used were: sit-stand-sit test, timed up & go test, 6-minute walk test, muscle strength measurement by means of dynamic dynamometer and short-form (SF)-36 questionnaire. RESULTS: Muscle strength, muscle endurance and quality of life regarding mental health increased statistically significantly in all 14 patients. There was no significant difference between the coenzyme Q10 and placebo groups regarding muscle strength, muscle endurance and quality of life. CONCLUSION:
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Authors | Katarina Skough, Charlott Krossén, Susanne Heiwe, Henning Theorell, Kristian Borg |
Journal | Journal of rehabilitation medicine
(J Rehabil Med)
Vol. 40
Issue 9
Pg. 773-5
(Oct 2008)
ISSN: 1651-2081 [Electronic] Sweden |
PMID | 18843432
(Publication Type: Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
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Chemical References |
- Vitamins
- Ubiquinone
- coenzyme Q10
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Topics |
- Administration, Oral
- Aged
- Double-Blind Method
- Exercise Therapy
- Female
- Humans
- Male
- Middle Aged
- Muscle Strength
(physiology)
- Muscle, Skeletal
(metabolism)
- Outcome Assessment, Health Care
- Physical Endurance
(physiology)
- Pilot Projects
- Postpoliomyelitis Syndrome
(metabolism, physiopathology, rehabilitation)
- Quality of Life
- Surveys and Questionnaires
- Ubiquinone
(administration & dosage, analogs & derivatives)
- Vitamins
(administration & dosage)
- Walking
(physiology)
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