Abstract |
A hemodialysis patient with hepatitis C virus infection developed painful blisters on her hands that burst spontaneously. She was found to have serum porphyrin levels >2000 nmol/L. A punch biopsy revealed subepidermal blistering with festooning of dermal papillae associated with a mixed inflammatory infiltrate. Based on the clinical, biochemical, and histologic findings, a diagnosis of porphyria cutanea tarda was made. Treatment was started with twice-weekly phlebotomy and oral hydroxychloroquine and significant clinical improvement resulted.
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Authors | Kurt Tarwater, Shamita Misra, Madhukar Misra |
Journal | Hemodialysis international. International Symposium on Home Hemodialysis
(Hemodial Int)
Vol. 12 Suppl 2
Pg. S38-42
(Oct 2008)
ISSN: 1492-7535 [Print] Canada |
PMID | 18837769
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Enzyme Inhibitors
- Hydroxychloroquine
|
Topics |
- Enzyme Inhibitors
(administration & dosage)
- Female
- Hepatitis C
(complications)
- Humans
- Hydroxychloroquine
(administration & dosage)
- Kidney Failure, Chronic
(complications, therapy)
- Middle Aged
- Phlebotomy
- Porphyria Cutanea Tarda
(complications, drug therapy)
- Renal Dialysis
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