| Abstract | This study reports the scintigraphy, histopathology, sole treatment with high-dose radioactive iodine and outcome of eight cases of feline thyroid carcinoma. Scintigraphic findings were variable and in 7/8 cases scintigraphic features could not reliably distinguish whether the thyroid tissue was malignant. Histopathology revealed typical criteria of malignancy in all cases, with mitotic activity described most frequently (7/8 cases), followed by infiltration of local tissues (4/8 cases). Cellular pleomorphism was infrequently observed. Single high-dose (1100MBq I(131)) radioiodine therapy was successful in 6/8 cases, with complete resolution of hyperthyroidism, and was associated with prolonged survival times (181-2381 days). Sole treatment with high-dose radioiodine is a safe and effective treatment for functional thyroid carcinoma. The prognosis for feline thyroid carcinoma successfully treated with radioiodine is good, with extended survival times commonly achieved. |
| Authors | Angie Hibbert, Tim Gruffydd-Jones, Esther L Barrett, Michael J Day, Andrea M Harvey
(Affiliation: The Feline Centre, Department of Clinical Veterinary Science, Division of Companion Animals, University of Bristol, Langford, Bristol, BS40 5DU, United Kingdom.)
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| Journal | Journal of feline medicine and surgery
(J Feline Med Surg)
Vol. 11
Issue 2
Pg. 116-24
(Feb 2009)
ISSN: 1098-612X England |
| PMID | 18835538
(Publication Type: Journal Article)
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