[Evaluation of the serological follow-up of newborn infants, carriers of HIV-1 antibodies].

Abstract

Serological follow-ups were performed in 19 newborns carrying HIV 1 antibodies over a period ranging between 9 and 62 months. Eight children developed AIDS ans 11 remained asymptomatic. Anti-HIV 1 antibodies were determined by ELISA and Western blot and p 24 antigen was detected by ELISA. Antibodies to HIV 1 disappeared in most children without AIDS symptoms between 10 and 12 months after birth, with antibodies against gp 41 being lost first. Children with AIDS remained positive during follow-up, although in 3 cases with positive was absent in all the asymptomatic children, while it was present in 75% of the patients with AIDS.

• Authors: G Codina Grau, C Juste Sánchez, T González Fuente, L Arcalis Arce, T Español Boren
• Journal: Anales espanoles de pediatria (An Esp Pediatr) Vol. 34 Issue 5 Pg. 339-41 (May 1991) ISSN: 0302-4342 [Print] Spain
• Vernacular Title: Valoración del seguimiento serológico en recién nacidos portadores de anticuerpos anti VIH 1.
• PMID: 1883106 (Publication Type: English Abstract, Journal Article)

Chemical References

• HIV Antibodies

Topics

• Acquired Immunodeficiency Syndrome (diagnosis, enzymology, epidemiology, immunology)
• Enzyme-Linked Immunosorbent Assay
• Follow-Up Studies
• HIV Antibodies (immunology)
• HIV Seropositivity (diagnosis, enzymology, immunology)
• Humans
• Infant, Newborn
• Spain (epidemiology)