Burkholderia pseudomallei meningitis following inadequate treatment of melioidotic mycotic aneurysm.

We report a 64-year-old man presenting with meningitis caused by Burkholderia pseudomallei predisposed by persistent aortic graft infection following inadequate treatment of a melioidotic mycotic aneurysm. The relapse of melioidosis presenting as acute meningitis is a unique event. Successful treatment of deep-seated melioidosis can only be achieved when robust antimicrobial therapy is combined with appropriate surgical debridement.
AuthorsM P Chlebicki, A Kurup, Y K Sin
JournalSingapore medical journal (Singapore Med J) Vol. 49 Issue 9 Pg. e219-21 (Sep 2008) ISSN: 0037-5675 [Print] Singapore
PMID18830523 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Anti-Bacterial Agents
  • Doxycycline
  • Administration, Oral
  • Aneurysm, Infected (complications, therapy)
  • Anti-Bacterial Agents (therapeutic use)
  • Aorta (microbiology, transplantation)
  • Blood Vessel Prosthesis Implantation (adverse effects)
  • Burkholderia Infections (etiology, microbiology, therapy)
  • Burkholderia pseudomallei (metabolism)
  • Doxycycline (therapeutic use)
  • Humans
  • Male
  • Melioidosis (complications, therapy)
  • Meningitis (etiology, microbiology, therapy)
  • Middle Aged
  • Recurrence
  • Treatment Outcome

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