Licensure of a diphtheria and tetanus toxoids and acellular pertussis adsorbed and inactivated poliovirus vaccine and guidance for use as a booster dose.

Abstract

On June 24, 2008, the Food and Drug Administration licensed a combined diphtheria and tetanus toxoids and acellular pertussis adsorbed (DTaP) and inactivated poliovirus (IPV) vaccine, DTaP-IPV (Kinrix, GlaxoSmithKline Biologicals, Rixensart, Belgium). Kinrix is licensed for use as the fifth dose of the DTaP vaccine series and the fourth dose of the IPV series in children aged 4-6 years whose previous DTaP vaccine doses were DTaP (Infanrix, GlaxoSmithKline) and/or DTaP-Hepatitis B-IPV (Pediarix, GlaxoSmithKline) for the first 3 doses and DTaP (Infanrix) for the fourth dose. DTaP-IPV administered to children aged 4-6 years would reduce by one the number of injections needed to complete DTaP and IPV immunization. This report summarizes the indications for Kinrix and provides guidance from the Advisory Committee on Immunization Practices (ACIP) for its use.

• Authors: Centers for Disease Control and Prevention (CDC)
• Journal: MMWR. Morbidity and mortality weekly report (MMWR Morb Mortal Wkly Rep) Vol. 57 Issue 39 Pg. 1078-9 (Oct 03 2008) ISSN: 1545-861X [Electronic] United States
• PMID: 18830212 (Publication Type: Journal Article, Practice Guideline)

Chemical References

• Diphtheria-Tetanus-acellular Pertussis Vaccines
• Poliovirus Vaccine, Inactivated
• Vaccines, Combined

Topics

• Child
• Child, Preschool
• Diphtheria-Tetanus-acellular Pertussis Vaccines (administration & dosage)
• Humans
• Immunization Schedule
• Immunization, Secondary
• Licensure
• Poliovirus Vaccine, Inactivated (administration & dosage)
• Vaccines, Combined