HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

[Accidental hypothermia in Switzerland (1980-1987)--case reports and prognostic factors].

Abstract
This retrospective study comprises 234 cases of accidental hypothermia (core temperature less than 35 degrees C) hospitalized in 95 Swiss clinics between 1980 and 1987. The most frequent accidents were alpine (n = 78) in origin, followed by cold exposure after injuries (n = 63) and suicide attempts (n = 43). Hypothermia was induced by cold air in 129 cases and by water in 47 cases. Patients were divided evenly between the degree of hypothermia: 75 mild (32-35 degrees C), 79 moderate (28-32 degrees C) and 66 severe (less than 28 degrees C). Among the survivors the coldest patient had a core temperature of 17.5 degrees C and the longest cardiac arrest with a favourable outcome lasted 4.75 hours. Out of the 234 patients 68 died (29%). We assessed all variables relative to outcome, in particular the mechanism of the accident, the mode of cooling, temperature, circulation, age and sex, underlying diseases, rewarming methods, medication and complications during the hospital course. All variables were tested in two multiple regression analysis models (retrospective model n = 181: prospective model n = 128) with regard to significance (p less than 0.05) and survival. Results are expressed with ODD's ratios (OR). The negative survival factors are asphyxia (OR 30), invasive rewarming methods (OR 20), slow rate of cooling (OR 10), asystole on arrival (OR 9), pulmonary edema or ARDS during hospitalization (OR 8), elevated serum potassium (OR 2/mmol/l) and age (OR 1.03/year). The positive survival factors are rapid cooling rate (OR 10), presence of ventricular fibrillation in cardiac arrest patients (OR 9) and presence of narcotics and/or alcohol during hypothermia (OR 5).(ABSTRACT TRUNCATED AT 250 WORDS)
AuthorsT Locher, B Walpoth, D Pfluger, U Althaus
JournalSchweizerische medizinische Wochenschrift (Schweiz Med Wochenschr) Vol. 121 Issue 27-28 Pg. 1020-8 (Jul 09 1991) ISSN: 0036-7672 [Print] Switzerland
Vernacular TitleAkzidentelle Hypothermie in der Schweiz (1980-1987)--Kasuistik und prognostische Faktoren.
PMID1882213 (Publication Type: English Abstract, Journal Article)
Topics
  • Adolescent
  • Adult
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Asphyxia (complications)
  • Blood Pressure
  • Body Temperature
  • Child
  • Child, Preschool
  • Female
  • Heart Arrest (physiopathology)
  • Hot Temperature (therapeutic use)
  • Humans
  • Hypothermia (epidemiology, physiopathology, therapy)
  • Infant
  • Logistic Models
  • Male
  • Middle Aged
  • Probability
  • Retrospective Studies
  • Survival Analysis
  • Switzerland (epidemiology)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: