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[The immediate results of the use of isometronidazole in the combination therapy of patients with lung cancer].

Abstract
The paper is devoted to assessment of isometronidazole tolerance, used as a radiosensitizer for preoperative irradiation of lung cancer patients, and to characterization of morphological postradiation changes in tissues of carcinomas removed at operation. Isometronidazole was shown to cause no severe side-effects in patients, improving considerably radiation injury of the tumor parenchyma.
AuthorsV V Zharkov, K Kh Merkle, M Gentshel, A V Furmanchuk, V P Kurchin, Iu E Demidchik, P I Moiseev
JournalMeditsinskaia radiologiia (Med Radiol (Mosk)) Vol. 36 Issue 7 Pg. 18-20 ( 1991) ISSN: 0025-8334 [Print] Russia (Federation)
Vernacular TitleNeposredstvennye rezul'taty primeneniia izometronidazola pri kombinirovannom lechenii bol'nykh rakom legkogo.
PMID1881282 (Publication Type: English Abstract, Journal Article)
Chemical References
  • Radiation-Sensitizing Agents
  • Metronidazole
  • isometronidazole
Topics
  • Adult
  • Combined Modality Therapy
  • Humans
  • Lung Neoplasms (drug therapy, radiotherapy, surgery)
  • Male
  • Metronidazole (analogs & derivatives, therapeutic use)
  • Middle Aged
  • Radiation-Sensitizing Agents (therapeutic use)

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