Abstract | BACKGROUND: AIMS: To validate a multivariable apnea risk prediction index ( MAPI) in stroke survivors and estimate SDB prevalence ( apnea-hypopnea index >or=10) in a community-based stroke cohort. METHODS: Self-reported sleep apnea symptoms, demographic and anthropometric data were obtained from a hospital-based (SCOPES II, n = 152) and a community-based (NEMESIS, n = 431) cohort at about 3 years after stroke. Logistic regression models for prediction of SDB using the MAPI were validated with home-based nocturnal polygraphic data recordings obtained in 74 SCOPES II participants. RESULTS: NEMESIS subjects (median age 76, females 45%) were older than SCOPES II subjects (median age 70, females 42%). SDB prevalence was 44.9% in the nocturnal polygraphy subset, and estimated as 44.1% (SCOPES II) and 50.6% (NEMESIS) using a modified MAPI. CONCLUSION: The MAPI can be reliably used in stroke cohorts and SDB affects about half of chronic stroke survivors.
|
Authors | Dora C Pearce, Dominique A Cadilhac, Robert J Pierce, Amanda G Thrift, Stephen David, Geoffrey A Donnan, SCOPES II Study Group |
Journal | Cerebrovascular diseases (Basel, Switzerland)
(Cerebrovasc Dis)
Vol. 26
Issue 4
Pg. 441-6
( 2008)
ISSN: 1421-9786 [Electronic] Switzerland |
PMID | 18799876
(Publication Type: Journal Article, Validation Study)
|
Copyright | Copyright 2008 S. Karger AG, Basel. |
Topics |
- Aged
- Aged, 80 and over
- Chronic Disease
- Female
- Follow-Up Studies
- Humans
- Logistic Models
- Male
- Middle Aged
- Polysomnography
- Predictive Value of Tests
- Prevalence
- Risk Factors
- Sleep Apnea Syndromes
(diagnosis, epidemiology)
- Stroke
(epidemiology)
|