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Immunotherapy of cancer with nonliving mycobacteria and cord factor (trehalose-6,6'-dimycolate) in aqueous medium.

Abstract
Heat-killed BCG, cord factor (trehalose-6,6'-dimycolate), or killed BCG plus cord factor in aqueous medium, admixed with tumor cells and injected into the skin of guinea pigs, inhibited the growth of a hepatocellular carcinoma. Intralesional administration of killed BCG or Mycobacterium kansasii coated with cord factor, in the same medium, caused regression of established tumors in 48 and 45% of the treated animals, respectively.
AuthorsA Bekierkunst
JournalJournal of the National Cancer Institute (J Natl Cancer Inst) Vol. 57 Issue 4 Pg. 963-4 (Oct 1976) ISSN: 0027-8874 [Print] United States
PMID187785 (Publication Type: Journal Article)
Topics
  • Animals
  • Carcinoma, Hepatocellular (therapy)
  • Guinea Pigs
  • Liver Neoplasms (therapy)
  • Neoplasms, Experimental (therapy)

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