Abstract | PURPOSE: CASE REPORT: A single observational case report of a 22-year-old Japanese male with evaporative dry eye and corneal epithelial disease because of lipid layer abnormality resulting from meibomian gland agenesis was treated successfully with low dose lipid base ointment application. DISCUSSION: The clinical features of the dry eye and ocular surface disease and management issues are discussed. CONCLUSION: Low dose lipid base ointment application may be a promising treatment modality for the ocular surface disease in ectrodactyly- ectodermal dysplasia (EEC)-clefting syndrome, which seems to help in alleviating the subjective complaints and in improving the objective clinical findings.
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Authors | Yu Ota, Yukihiro Matsumoto, Murat Dogru, Eiki Goto, Yuichi Uchino, Koji Endo, Kazuo Tsubota |
Journal | Optometry and vision science : official publication of the American Academy of Optometry
(Optom Vis Sci)
Vol. 85
Issue 9
Pg. E795-801
(Sep 2008)
ISSN: 1538-9235 [Electronic] United States |
PMID | 18772710
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Lipids
- Ointments
- Ophthalmic Solutions
- Ofloxacin
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Topics |
- Adult
- Corneal Diseases
(drug therapy, etiology, metabolism)
- Dry Eye Syndromes
(drug therapy, etiology, metabolism)
- Ectodermal Dysplasia
(complications, genetics)
- Eye Abnormalities
(complications, genetics)
- Foot Deformities, Congenital
(complications, genetics)
- Hand Deformities, Congenital
(complications, genetics)
- Humans
- Lipids
(deficiency)
- Male
- Meibomian Glands
(abnormalities)
- Ofloxacin
(administration & dosage)
- Ointments
- Ophthalmic Solutions
(administration & dosage)
- Syndrome
- Tears
(metabolism)
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