Abstract | BACKGROUND: METHODS: In a randomized double-blinded study, we evaluated 80 healthy children, aged 4-12 years, who underwent tonsillectomy with or without adenoidectomy. After anesthesia was induced by inhalation of sevoflurane, 0.15 mg x kg(-1) dexamethasone and 2 microg x kg(-1) fentanyl was administered i.v. to all patients. The patients in the dexamethasone plus propofol group received 1 mg x kg(-1) propofol before intubation and continuously after intubation at a rate of 20 microg x kg(-1) x min(-1) until the surgery was completed. Data for postoperative vomiting were grouped into the following time periods: 0-4 and 4-24 h. Data were analyzed using a Student's t-test and chi-squared analysis. RESULTS: CONCLUSION:
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Authors | Ali Fuat Erdem, Ozgur Yoruk, Haci Ahmet Alici, Mehmet Cesur, Canan Atalay, Enver Altas, Husnu Kursad, Mustafa Sahin Yuksek |
Journal | Paediatric anaesthesia
(Paediatr Anaesth)
Vol. 18
Issue 9
Pg. 878-83
(Sep 2008)
ISSN: 1460-9592 [Electronic] France |
PMID | 18768048
(Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial)
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Chemical References |
- Anesthetics, Intravenous
- Antiemetics
- Ondansetron
- Dexamethasone
- Propofol
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Topics |
- Anesthetics, Intravenous
(administration & dosage)
- Antiemetics
(administration & dosage)
- Child
- Child, Preschool
- Dexamethasone
(administration & dosage)
- Double-Blind Method
- Drug Therapy, Combination
- Female
- Humans
- Male
- Ondansetron
(therapeutic use)
- Postoperative Nausea and Vomiting
(prevention & control)
- Propofol
(administration & dosage)
- Tonsillectomy
(adverse effects)
- Treatment Outcome
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