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Performance of the BioPlex 2200 Autoimmune Vasculitis kit.

AbstractThe BioRad BioPlex 2200 Vasculitis kit demonstrates excellent relative sensitivity and relative specificity for the semi-quantitative detection of IgG autoantibodies to MPO, PR3 and GBM. The fully-automated platform simultaneously measures three analytes in a single tube, offering superior advantage in speed and ease of use over current assays. The availability of a fully-automated platform with 24-hour availability for these three antibodies may be of considerable value in the differential diagnosis of patients with rapidly progressive glomerulonephritis.
AuthorsRavi Kaul, Kim Johnson, Heidi Scholz, Greg Marr (Affiliation: BioPlex Division, Clinical Diagnostics Group, Bio-Rad Laboratories, Hercules, California 94547, USA. ravi_kaul at bio-rad.com)
JournalAutoimmunity reviews (Autoimmun Rev) Vol. 8 Issue 3 Pg. 224-7 (Jan 2009) ISSN: 1873-0183 [Electronic] Netherlands
PMID18718876 (Publication Type: Journal Article, Review)
Chemical References
  • Antibodies, Antineutrophil Cytoplasmic
  • Granulocyte Colony Stimulating Factor, Recombinant
  • Interleukin-3
  • Reagent Kits, Diagnostic
  • Recombinant Fusion Proteins
  • myelopoietin
  • Peroxidase
Topics
  • Antibodies, Antineutrophil Cytoplasmic (immunology)
  • Diagnosis, Differential
  • Diagnostic Equipment
  • Enzyme-Linked Immunosorbent Assay
  • Flow Cytometry
  • Glomerulonephritis (diagnosis, immunology)
  • Granulocyte Colony Stimulating Factor, Recombinant (immunology)
  • Humans
  • Immunomagnetic Separation
  • Interleukin-3 (immunology)
  • Peroxidase (immunology)
  • Reagent Kits, Diagnostic
  • Recombinant Fusion Proteins (immunology)
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Vasculitis (diagnosis, immunology)

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