Compound heterozygosity for the Cretan type of non-deletional hereditary persistence of fetal hemoglobin and beta-thalassemia or Hb Sabine confirms the functional role of the Agamma -158 C>T mutation in gamma-globin gene transcription.

• Authors: Panagoula Kollia, Angelos Kalamaras, Christos Chassanidis, Maria Samara, Nikolaos K Vamvakopoulos, Milena Radmilovic, Sonja Pavlovic, Manoussos N Papadakis, George P Patrinos
• Journal: Blood cells, molecules & diseases (Blood Cells Mol Dis) 2008 Nov-Dec Vol. 41 Issue 3 Pg. 263-4 ISSN: 1096-0961 [Electronic] United States
• PMID: 18718799 (Publication Type: Letter)

Chemical References

• Hemoglobins, Abnormal
• gamma-Globins
• hemoglobin Sabine
• Fetal Hemoglobin

Topics

• Adult
• Female
• Fetal Hemoglobin (genetics)
• Hemoglobins, Abnormal (genetics)
• Heterozygote
• Humans
• Male
• Point Mutation
• beta-Thalassemia (genetics)
• gamma-Globins (genetics)