Abstract |
Orbital involvement in chronic lymphocytic leukemia (CLL) is highly unusual and most commonly involves hemorrhage or soft tissue infiltration in advanced disease. We report a case of rapid onset bilateral orbital muscle infiltration as the presenting feature of early stage CLL. In addition, we demonstrate clinico-pathological correlation with an identical chronic B-cell lymphocytic infiltrate in both orbit and bone marrow, with good response of the orbital disease to local radiotherapy.
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Authors | Yashin D Ramkissoon, Richard W J Lee, Rizwan Malik, James D Hsuan, Mike J Potts |
Journal | Orbit (Amsterdam, Netherlands)
(Orbit)
Vol. 27
Issue 4
Pg. 293-5
( 2008)
ISSN: 1744-5108 [Electronic] England |
PMID | 18716967
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Antigens, CD
- Glucocorticoids
- Methylprednisolone
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Topics |
- Aged
- Antigens, CD
(analysis)
- Combined Modality Therapy
- Functional Laterality
- Glucocorticoids
(therapeutic use)
- Humans
- Immunophenotyping
- Leukemia, Lymphocytic, Chronic, B-Cell
(drug therapy, pathology, radiotherapy)
- Leukemic Infiltration
(drug therapy, pathology, radiotherapy)
- Magnetic Resonance Imaging
- Male
- Methylprednisolone
(therapeutic use)
- Oculomotor Muscles
(drug effects, pathology)
- Orbital Neoplasms
(drug therapy, pathology, radiotherapy)
- Radiotherapy
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