Abstract | SUMMARY: A neuroma-in-continuity is a neuroma that results from failure of the regenerating nerve growth cone to reach peripheral targets. It occurs within an intact nerve in response to internally damaged fascicles, resulting in a distal portion of the nerve that no longer functions properly. Management of neuromas-in-continuity is challenging. Chemical methods, and microsurgical techniques including fascicular ligation, and burying into muscle and bone have been reported to prevent neuroma-in-continuity formation. The purpose of this article is to present novel techniques for neuroma-in-continuity management, and to discuss the related literature.
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Authors | Andreas F Mavrogenis, Kitty Pavlakis, Anna Stamatoukou, Panayiotis J Papagelopoulos, Stamatios Theoharis, Aristidis B Zoubos, Zijie Zhang, Panayotis N Soucacos |
Journal | Injury
(Injury)
Vol. 39 Suppl 3
Pg. S43-8
(Sep 2008)
ISSN: 1879-0267 [Electronic] Netherlands |
PMID | 18715561
(Publication Type: Journal Article, Review)
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Chemical References |
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Topics |
- Animals
- Humans
- Immunotoxins
(therapeutic use)
- Microsurgery
(methods)
- Neuroma
(etiology, therapy)
- Neurosurgical Procedures
(methods)
- Neurotoxins
(therapeutic use)
- Peripheral Nerve Injuries
- Peripheral Nervous System Neoplasms
(etiology, therapy)
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