Arginine vasopressin in the treatment of vasodilatory septic shock.

Abstract

Vasodilatory septic shock is characterized by profound vasodilation of the peripheral circulation, relative refractoriness to catecholamines and a relative deficiency of the posterior pituitary hormone, vasopressin. Arginine vasopressin is effective in restoring vascular tone in vasodilatory septic shock and may be associated with decreased mortality in less severe septic shock as well as improved mortality and decreased renal failure in septic shock patients at risk for renal failure.

• Authors: Cheryl L Holmes, Keith R Walley
• Journal: Best practice & research. Clinical anaesthesiology (Best Pract Res Clin Anaesthesiol) Vol. 22 Issue 2 Pg. 275-86 (Jun 2008) ISSN: 1753-3740 [Print] Netherlands
• PMID: 18683474 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Review)

Chemical References

• Vasoconstrictor Agents
• Vasopressins
• Arginine Vasopressin

Topics

• Animals
• Arginine Vasopressin (therapeutic use)
• Clinical Trials as Topic
• Humans
• Shock, Septic (drug therapy, physiopathology)
• Vasoconstrictor Agents (therapeutic use)
• Vasodilation (drug effects, physiology)
• Vasopressins (deficiency)