Collapsing glomerulopathy and haemophagocytic syndrome related to malaria: a case report.

Abstract

Authors report a 37-year-old Senegalese woman with no known history of nephropathy who was admitted for fever related to malaria, severe acute renal failure requiring dialysis with nephrotic syndrome. Biological examinations and bone marrow aspiration showed hemophagocytic syndrome. A kidney biopsy found a 'collapsing glomerulopathy' (CG). A protracted course of steroids yielded a complete, unexpected remission of the nephrotic syndrome and renal function was normal at 18 months.

• Authors: Abdou Niang, Samira Elfajri Niang, El Hadji Fary Ka, Mamadou M Ka, Boucar Diouf
• Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association (Nephrol Dial Transplant) Vol. 23 Issue 10 Pg. 3359-61 (Oct 2008) ISSN: 1460-2385 [Electronic] England
• PMID: 18676345 (Publication Type: Case Reports, Journal Article)

Chemical References

• Glucocorticoids
• Methylprednisolone

Topics

• Adult
• Female
• Glucocorticoids (therapeutic use)
• Humans
• Lymphohistiocytosis, Hemophagocytic (etiology)
• Malaria, Falciparum (complications)
• Methylprednisolone (therapeutic use)
• Nephrotic Syndrome (etiology, pathology, physiopathology, therapy)
• Renal Dialysis