De novo autoimmune hepatitis following liver transplantation: a case report.

Abstract

De novo autoimmune hepatitis (AIH), a rare disorder first described in 1998, appears in patients with liver transplants due to autoimmune and nonautoimmune etiologies. De novo AIH occurs in 2.5% to 3.4% of allografts; children seem to have a predilection for this syndrome. We have present herein a case of a liver allograft recipient who developed chronic hepatitis associated with autoimmune features outlining the clinical course, liver histology, and response to treatment.

• Authors: P Di Cocco, A Barletta, K Clemente, M D'Angelo, S Greco, C Mazzotta, G Orlando, V Rizza, A Famulari, A Grimaldi, F Pisani
• Journal: Transplantation proceedings (Transplant Proc) 2008 Jul-Aug Vol. 40 Issue 6 Pg. 2073-4 ISSN: 0041-1345 [Print] United States
• PMID: 18675134 (Publication Type: Case Reports, Journal Article)

Chemical References

• Glucocorticoids
• Prednisolone
• Aspartate Aminotransferases
• Alanine Transaminase

Topics

• Alanine Transaminase (blood)
• Aspartate Aminotransferases (blood)
• Carcinoma, Hepatocellular (complications, surgery)
• Follow-Up Studies
• Glucocorticoids (therapeutic use)
• Hepatitis, Autoimmune (diagnosis, drug therapy, pathology)
• Humans
• Liver Cirrhosis, Alcoholic (complications, surgery)
• Liver Failure (etiology, surgery)
• Liver Neoplasms (complications, surgery)
• Liver Transplantation (adverse effects, pathology)
• Male
• Middle Aged
• Postoperative Complications (diagnosis, drug therapy, pathology)
• Prednisolone (therapeutic use)
• Treatment Outcome