[Integrative medicinal therapy on herpes zoster in middle and old aged patients].

Abstract

OBJECTIVE:

To study the therapeutic effect of integrative medicinal therapy with Qinzhu Liangxue Mixture (QLM) in combined with valaciclovir on herpes zoster (HZ) in middle and old aged patients.

METHODS:

Ninety-seven HZ patients were randomly assigned to three groups and treated respectively with QLM alone (A), valaciclovir alone (B) and QLM plus valaciclovir (C). Times for stopping newly appeared blisters, scabbing relieving pain, and curing, as well as incidence rate of postherpetic neuralgia (PHN) after treatment were evaluated. Patients' symptoms and signs were scored before and after treatment.

RESULTS:

Time for appeaed newly blister and scabbing was shorter in Group B than in Group A; time for relieving pain and curing was shorter in Group C than in Group A; and the PHN incidence rate in Group C was the lowest.

CONCLUSION:

Valaciclovir can control the skin rash of HZ with quicker initiating time, and QLM can effectively relieve pain, the combined use with the two drugs can decrease the incidence rate of PHN availably.

• Authors: Yi-Fei Wang, Ming Zhang, Lin Geng
• Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine (Zhongguo Zhong Xi Yi Jie He Za Zhi) Vol. 28 Issue 5 Pg. 451-3 (May 2008) ISSN: 1003-5370 [Print] China
• PMID: 18672776 (Publication Type: Journal Article, Randomized Controlled Trial)

Chemical References

• Analgesics
• Antiviral Agents
• Drugs, Chinese Herbal
• qinzhu liangxue
• Valine
• Valacyclovir
• Acyclovir

Topics

• Acyclovir (analogs & derivatives, therapeutic use)
• Aged
• Analgesics (therapeutic use)
• Antiviral Agents (therapeutic use)
• Drug Therapy, Combination
• Drugs, Chinese Herbal (therapeutic use)
• Herpes Zoster (drug therapy)
• Humans
• Integrative Medicine
• Middle Aged
• Valacyclovir
• Valine (analogs & derivatives, therapeutic use)