[Inhibitor factors in the serum of patients with the AIDS-related complex].

Abstract

The data on the presence of factors blocking the reaction of E-rosette formation and leukocyte chemotaxis in the blood sera of patients with AIDS-related complex (ARC) and HIV-positive donors are presented. Most frequently the blocking of E-rosette formation coincided with the presence of a inhibiting effect on the migration capacity of leukocytes. This blocking activity was not linked with the presence of C-reactive protein in the circulation stream. The treatment of ARC patients with plasmapheresis and/or travolol was accompanied either by the disappearance of blocking activity or by the appearance of activity stimulating E-rosette formation.

• Authors: B V Pinegin, M Z Saidov, O F Eremina, A M Borisova, R M Khaitov
• Journal: Zhurnal mikrobiologii, epidemiologii i immunobiologii (Zh Mikrobiol Epidemiol Immunobiol) Issue 2 Pg. 26-7 (Feb 1991) ISSN: 0372-9311 [Print] Russia (Federation)
• Vernacular Title: Ingibitornye faktory v syvorotke bol'nykh so SPID-assotsiirovannym kompleksom.
• PMID: 1867028 (Publication Type: English Abstract, Journal Article)

Chemical References

• travolol
• Penicillamine

Topics

• AIDS-Related Complex (immunology, therapy)
• Adolescent
• Adult
• Cell Migration Inhibition
• Female
• HIV Seropositivity (immunology, therapy)
• HIV-1
• Humans
• Immune Tolerance (immunology)
• Male
• Middle Aged
• Penicillamine (analogs & derivatives, therapeutic use, toxicity)
• Plasmapheresis
• Rosette Formation