Abstract | BACKGROUND: METHODS: A child with CML in lymphoid blast crisis was diagnosed by complete hematological and bone marrow examination. There was no central nervous system (CNS) leukemia at presentation. The child was treated with IM at a daily dose of 400 mg. RESULTS: The child showed remission after IM administration for 28 days and remained in remission till 59 days. On day 59 she experienced headache and vomiting. Results of cerebrospinal fluid taken for cytopathology showed CNS leukemia. MCP 841 protocol for ALL and weekly intrathecal triple therapy (ITT) was given. CONCLUSIONS:
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Authors | Vasantha Thavaraj, Rachna Seth |
Journal | World journal of pediatrics : WJP
(World J Pediatr)
Vol. 4
Issue 2
Pg. 145-7
(May 2008)
ISSN: 1708-8569 [Print] Switzerland |
PMID | 18661773
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Anti-Inflammatory Agents
- Benzamides
- Piperazines
- Pyrimidines
- Cytarabine
- Imatinib Mesylate
- Hydrocortisone
- Methotrexate
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Topics |
- Anti-Inflammatory Agents
(administration & dosage)
- Antineoplastic Combined Chemotherapy Protocols
(therapeutic use)
- Benzamides
- Blast Crisis
(complications, diagnosis, drug therapy)
- Blood Cell Count
- Central Nervous System Neoplasms
(diagnosis, etiology, prevention & control)
- Chemoprevention
(methods)
- Child
- Clinical Protocols
- Cytarabine
(administration & dosage)
- Drug Therapy, Combination
- Female
- Humans
- Hydrocortisone
(administration & dosage)
- Imatinib Mesylate
- Injections, Spinal
- Methotrexate
(therapeutic use)
- Piperazines
(administration & dosage)
- Precursor Cell Lymphoblastic Leukemia-Lymphoma
(diagnosis, drug therapy, etiology)
- Pyrimidines
(administration & dosage)
- Remission Induction
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