[Use of chlotazol as an immunomodulating agent in chronic bronchitis].

Abstract

A positive immunomodulatory effect was found in chronic bronchitis patients examined immunologically before and after treatment including chlotazol. T- and B-cell immunity recovered, clinical condition of the patients improved. A combination of known antimicrobial and antiinflammatory effects with an uncovered immunomodulatory one made chlotazol a valuable modality in the treatment of chronic bronchitis associated with secondary immune deficiency.

• Authors: A I Kleĭner, L M Shmuter, V M Makotchenko, V A Efremova, Ia I Khodzhaĭ, V S Trukh
• Journal: Klinicheskaia meditsina (Klin Med (Mosk)) Vol. 69 Issue 4 Pg. 58-60 (Apr 1991) ISSN: 0023-2149 [Print] Russia (Federation)
• Vernacular Title: Primenenie khlotazola v kachestve immunomoduliruiushchego sredstva pri khronicheskom bronkhite.
• PMID: 1865653 (Publication Type: English Abstract, Journal Article)

Chemical References

• Adjuvants, Immunologic
• Anti-Inflammatory Agents, Non-Steroidal
• Thiazoles
• Chloral Hydrate
• chlotazol

Topics

• Adjuvants, Immunologic (therapeutic use)
• Anti-Inflammatory Agents, Non-Steroidal (therapeutic use)
• B-Lymphocytes (immunology, pathology)
• Bronchitis (drug therapy, immunology)
• Chloral Hydrate (therapeutic use)
• Chronic Disease
• Humans
• Leukocyte Count (drug effects)
• Lymphopenia (drug therapy, etiology)
• T-Lymphocytes (immunology, pathology)
• Thiazoles (therapeutic use)