Abstract | OBJECTIVES: MATERIALS AND METHODS: Nineteen consecutive patients were evaluated at baseline, at a mean of 1 year, then at a mean of 7 years after DBS using Tremor Rating Scale, Mini Mental Test, ADL Taxonomy, Nottingham Health Profile, Life Satisfaction Checklist, Visual Analogue Scale and interview. RESULTS: There was a decrease of DBS efficacy on tremor between 1 and 7 years post-operatively. The marked improvement in ADL at 1 year was no longer sustained at long-term, except for the ability to eat. Social life remained improved. CONCLUSION: Although there is a decrease of DBS effect on tremor at 7 years, and even though further ageing and co-morbidities may impact on the well-being of patients, there is still relevant benefit of DBS on few aspects of ADL and HRQoL in patients with ET.
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Authors | G-M Hariz, P Blomstedt, L-O D Koskinen |
Journal | Acta neurologica Scandinavica
(Acta Neurol Scand)
Vol. 118
Issue 6
Pg. 387-94
(Dec 2008)
ISSN: 1600-0404 [Electronic] Denmark |
PMID | 18616684
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Topics |
- Activities of Daily Living
(psychology)
- Aged
- Aged, 80 and over
- Deep Brain Stimulation
- Disability Evaluation
- Essential Tremor
(physiopathology, psychology, therapy)
- Female
- Humans
- Male
- Neuropsychological Tests
- Quality of Life
(psychology)
- Surveys and Questionnaires
- Thalamus
(anatomy & histology, physiopathology)
- Time
- Treatment Outcome
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