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Long-term effect of deep brain stimulation for essential tremor on activities of daily living and health-related quality of life.

AbstractOBJECTIVES:
To report long-term effects of thalamic deep brain stimulation (DBS) on activities of daily living (ADL) and health-related quality of life (HRQoL) in patients with essential tremor (ET).
MATERIALS AND METHODS:
Nineteen consecutive patients were evaluated at baseline, at a mean of 1 year, then at a mean of 7 years after DBS using Tremor Rating Scale, Mini Mental Test, ADL Taxonomy, Nottingham Health Profile, Life Satisfaction Checklist, Visual Analogue Scale and interview.
RESULTS:
There was a decrease of DBS efficacy on tremor between 1 and 7 years post-operatively. The marked improvement in ADL at 1 year was no longer sustained at long-term, except for the ability to eat. Social life remained improved.
CONCLUSION:
Although there is a decrease of DBS effect on tremor at 7 years, and even though further ageing and co-morbidities may impact on the well-being of patients, there is still relevant benefit of DBS on few aspects of ADL and HRQoL in patients with ET.
AuthorsG-M Hariz, P Blomstedt, L-O D Koskinen
JournalActa neurologica Scandinavica (Acta Neurol Scand) Vol. 118 Issue 6 Pg. 387-94 (Dec 2008) ISSN: 1600-0404 [Electronic] Denmark
PMID18616684 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Topics
  • Activities of Daily Living (psychology)
  • Aged
  • Aged, 80 and over
  • Deep Brain Stimulation
  • Disability Evaluation
  • Essential Tremor (physiopathology, psychology, therapy)
  • Female
  • Humans
  • Male
  • Neuropsychological Tests
  • Quality of Life (psychology)
  • Surveys and Questionnaires
  • Thalamus (anatomy & histology, physiopathology)
  • Time
  • Treatment Outcome

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